External Quality Assessment for C-reactive protein
Welcome to the 9th Workshop on Proficiency testing in Analytical Chemistry, Microbiology and Laboratory Medicine 9-12 October, 2017 in Portorož, Slovenia
Labquality´s international external quality assessment programme 2018 is available at the exhibition of the workshop. New EQA programme covers all main areas of laboratory medicine and provides full support to ISO15189 requirements. Please visit our booth at Eurachem PT workshop and get your own copy of our programme or you can download the pdf version from the link below.
EQA for C-reactive protein
CRP is one of the most analyzed parameters in clinical laboratories and point-of-care sites. Labquality has organized external quality assessment schemes for CRP since 1983. At the moment we have two separate EQA schemes for CRP. One for clinical chemistry analyzers and another for POCT CRP meters. Both schemes have two commutable, liquid samples and appropriate number of participants. Please find scheme details from the links below.
Traceability and method groups of C-reactive protein results
Poster by Päivi Ranta, Ulla Tiikkainen, Gitte Henriksen, Anita Latvala and Kari Åkerman is presented in Eurachem PT workshop in Portorož. Päivi Ranta and Ulla Tiikkainen from Labquality are available for additional questions between 9th and 12th of October at the workshop.
Introduction
C‑reactive protein (CRP) is the most sensitive of the acute phase reactants and its concentration increases rapidly in inflammatory reactions. According to the manufacturers CRP results are traceable to the three certified reference materials (CRM): ERM® – DA470, ERM® – DA472/IFCC and ERM® – DA474/IFCC which all are traceable to SI via ERM® – DA470 (1). The traceability of results enables the use of common biological reference intervals in laboratories worldwide. Patient results can also be compared over time and between hospitals and countries.
Labquality has organized external quality assurance schemes (EQA) for CRP measurements since 1983. In these schemes results are processed in method groups
and the method group mean is used as the assigned value. The idea of this poster was to investigate whether it would be possible to handle the results in one group since traceability of all the results is to the same ERM® – DA470. In theory no differences exist between measurement methods. Moreover, we wanted to examine the usage of different assigned values i.e. method group mean and transferred reference value from ERM® – DA474/IFCC and their influence on the evaluation of the performance of the laboratories.